Fiberoptic microneedles: Novel optical diffusers for interstitial delivery of therapeutic light

Abstract

Photothermal therapies have limited efficacy and application due to the poor penetration depth of light inside tissue. In earlier work, we described the development of novel fiberoptic microneedles to provide a means to mechanically penetrate dermal tissue and deliver light directly into a localized target area. This paper presents an alternate fiberoptic microneedle design with the capability of delivering more diffuse, but therapeutically useful photothermal energy. Laser lipolysis is envisioned as a future clinical application for this design.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 17, 2011
Source ID
10.1002/lsm.21129

Entities

People

  • Christopher G. Rylander
  • David C. Grant
  • John H. Rossmeisl Jr.
  • John L. Robertson
  • Marissa Nichole Rylander
  • Mehmet A. Kosoglu
  • R. Lyle Hood
  • Yong Xu

Organizations

  • Air Force Office of Scientific Research
  • National Science Foundation

Tags

Fields of Study

  • Physics

Readers

  • Molecular and Cellular Biology
  • Nanoscale Plasmonic Nanotechnology
  • Optical Fiber Sensing and Electromagnetic Propagation.

Technology Areas

  • Directed Energy