Low‐Level Laser Therapy for Closed‐Head Traumatic Brain Injury in Mice: Effect of Different Wavelengths
Abstract
Traumatic brain injury (TBI) affects millions worldwide and is without effective treatment. One area that is attracting growing interest is the use of transcranial low‐level laser therapy (LLLT) to treat TBI. The fact that near‐infrared light can penetrate into the brain would allow non‐invasive treatment to be carried out with a low likelihood of treatment‐related adverse events. LLLT may treat TBI by increasing respiration in the mitochondria, causing activation of transcription factors, reducing inflammatory mediators and oxidative stress, and inhibiting apoptosis.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 24, 2012
- Source ID
- 10.1002/lsm.22003
Entities
People
- Liyi Huang
- Michael J. Whalen
- Michael R. Hamblin
- Qiuhe Wu
- Saphala Dhital
- Sulbha K. Sharma
- Takahiro Ando
- Tao Xu
- Tianghong Dai
- Weijun Xuan
- Ying‐ying Huang
Organizations
- Air Force Office of Scientific Research
- National Institutes of Health