Light‐activated photosealing with human amniotic membrane strengthens bowel anastomosis in a hypotensive, trauma‐relevant swine model

Abstract

Gastrointestinal anastomotic leakage is a dreaded complication despite advancements in surgical technique. Photochemical tissue bonding (PTB) is a method of sealing tissue surfaces utilizing photoactive dye. We evaluated if crosslinked human amniotic membrane (xHAM) photosealed over the enteroenterostomy would augment anastomotic strength in a trauma‐relevant swine hemorrhagic shock model.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 19, 2021
Source ID
10.1002/lsm.23485

Entities

People

  • Benjamin B Scott
  • Mark Randolph
  • Robert W Redmond
  • Ruby C. Wu
  • Ying Wang

Organizations

  • Harvard Medical School

Tags

Fields of Study

  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Trauma Surgery or Emergency Medicine.