Zipping Polymers into Nanoparticles via Intrachain Alternating Radical Copolymerization

Abstract

The synthesis of single‐chain nanoparticles (SCNP) via the intrachain radical homopolymerization and alternating copolymerization of pendant styrene or stilbene units is reported. In the presence of a radical initiator, styrene‐functionalized polymers undergo intrachain cross‐linking to form SCNP; however, when an electron deficient monomer such as maleic anhydride is added, interchain coupling occurs. For the stilbene‐functionalized polymer, no homopolymerization of pendant stilbene units is observed, but copolymerization initiated in the presence of maleic anhydride or N‐ethyl maleimide results in nanoparticle formation. Fluorescent SCNP are synthesized using N‐(1‐pyrene)maleimide. Stilbene is known to undergo alternating copolymerization with these electron‐deficient monomers, providing a new method for synthesizing cross‐linked particles with simple alternating sequences while simultaneously installing functionality and tuning the particle size and density. image

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 09, 2015
Source ID
10.1002/macp.201500355

Entities

People

  • Christopher K. Lyon
  • Ellen O. Hill
  • Erik B. Berda

Organizations

  • Army Research Office
  • National Aeronautics and Space Administration
  • University of New Hampshire

Tags

Fields of Study

  • Chemistry

Readers

  • Nanocomposite Materials Science
  • Polymer Science and Technology

Technology Areas

  • Biotechnology
  • Microelectronics