Biocatalytic Stimuli‐Responsive Asymmetric Triblock Terpolymer Membranes for Localized Permeability Gating

Abstract

The functionalization with phosphotriesterase of poly(isoprene‐b‐styrene‐b‐4‐vinylpyridine)‐based nanoporous membranes fabricated by self‐assembly and nonsolvent induced phase separation (SNIPS) is shown to enable dynamically responsive membranes capable of substrate‐specific and localized gating response. Integration of the SNIPS process with macroporous nylon support layers yields mechanically robust textile‐type films with high moisture vapor transport rates that display rapid and local order‐of‐magnitude modulation of permeability. The simplicity of the fabrication process that is compatible with large‐area fabrication along with the versatility and efficacy of enzyme reactivity offers intriguing opportunities for engineered biomimetic materials that are tailored to respond to a complex range of external parameters, providing sensing, protection, and remediation capabilities.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 15, 2017
Source ID
10.1002/marc.201700364

Entities

People

  • David M Wilson
  • Ilhem F. Hakem
  • Jennifer L. Poole
  • Jeremy Walker
  • Larry Takiff
  • Lawrence F. Hancock
  • Michael R Bockstaller
  • Qi Zhang
  • Rachel Ferebee
  • Rachel Mika Dorin
  • Scott Donahue
  • Ulrich Wiesner
  • Yibei Gu
  • Yuk Mun Li
  • Zhao Lu

Organizations

  • Carnegie Mellon University
  • Cornell University
  • Defense Threat Reduction Agency
  • FLIR Systems

Tags

Readers

  • Nanocomposite Materials Science
  • Nanoscale Plasmonic Nanotechnology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology