Inflammation and Parkinson's disease pathogenesis

Abstract

Inflammation is a neuropathological feature of parkinsonian brains and also in experimental models of the disease. It is believed that activated glial cells, which compose the majority of this inflammatory response contribute to the neurodegenerative process through the production of toxic molecules. Therapeutic strategies geared toward reducing inflammation and inhibiting the production of these glial‐derived toxic molecules may be a promising neuroprotective strategy for the treatment of Parkinson's disease and related conditions. © 2010 Movement Disorder Society

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2010
Source ID
10.1002/mds.22638

Entities

People

  • Serge Przedborski

Organizations

  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Oncology
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.