Interaction between caffeine and polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2) on Parkinson's disease risk

Abstract

Background: Caffeine intake has been inversely associated with Parkinson's disease (PD) risk. This relationship may be modified by polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2), but the results of previous studies have been inconsistent.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jan 10, 2018
• Source ID: 10.1002/mds.27279

Entities

People

• Alberto Ascherio
• Iris Y. Kim
• Katherine C. Hughes
• Marian T. Hannan
• Marjorie L. Mccullough
• Michael A Schwarzschild
• Rebecca A. Betensky
• Xiang Gao
• Éilis J. O'reilly

Organizations

• American Cancer Society
• Harvard Medical School
• Harvard University
• Massachusetts General Hospital
• National Institutes of Health
• Pennsylvania State University
• United States Department of Defense
• University College Cork

Tags

Fields of Study

• Biology
• Chemistry
• Medicine

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