Association of brain heptachlor epoxide and other organochlorine compounds with lewy pathology
Abstract
Organochlorine pesticides are associated with an increased risk of Parkinson's disease. A preliminary analysis from the Honolulu‐Asia Aging Study suggested that heptachlor epoxide, a metabolite from an organochlorine pesticide extensively used in Hawaii, may be especially important. This was a cross sectional analysis to evaluate the association of heptachlor epoxide and other organochlorine compounds with Lewy pathology in an expanded survey of brain organochlorine residues from the longitudinal Honolulu‐Asia Aging Study.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 30, 2018
- Source ID
- 10.1002/mds.27594
Entities
People
- Caroline M. Tanner
- Chris Zarow
- G. Webster Ross
- Helen Petrovitch
- Jane H. Uyehara‐lock
- John E. Duda
- Kamal H. Masaki
- Lenore J. Launer
- Lon R. White
- Robert D. Abbott
- William B. Studabaker
Organizations
- Korea University
- Kuakini Medical Center
- National Institute of Neurological Disorders and Stroke
- National Institute on Aging
- Pacific Health Research and Education Institute
- United States Army Medical Research and Development Command
- University of California, San Francisco
- University of Hawaiʻi System
- University of Pennsylvania
- University of Southern California
- Veterans Health Administration