The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease

Abstract

PD is a complex polygenic disorder. In recent years, several genes from the endocytic membrane‐trafficking pathway have been suggested to contribute to disease etiology. However, a systematic analysis of pathway‐specific genetic risk factors is yet to be performed.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 24, 2019
Source ID
10.1002/mds.27614

Entities

People

  • Andrew B. Singleton
  • Cornelis Blauwendraat
  • Dan Vitale
  • Jesse Raphael Gibbs
  • Kimberley J Billingsley
  • Lasse Pihlstrøm
  • Luis Bonet‐ponce
  • Mark R Cookson
  • Mike A. Nalls
  • Sara Bandres‐ciga
  • Sara Saez‐atienzar
  • The International Parkinson's Disease Genomics Consortium (ipdgc)
  • Ziv Gan-Or

Organizations

  • McGill University
  • National Institutes of Health
  • Oslo University Hospital
  • United States Department of Defense
  • University of Liverpool
  • University of Tartu

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Immunology and Pathology
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.

Technology Areas

  • Biotechnology