Blinded RT‐QuIC Analysis of α‐Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients

Abstract

An unmet clinical need in Parkinson's disease (PD) is to identify biomarkers for diagnosis, preferably in peripherally accessible tissues such as skin. Immunohistochemical studies have detected pathological α‐synuclein (αSyn) in skin biopsies from PD patients albeit sensitivity needs to be improved.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Sep 22, 2020
• Source ID: 10.1002/mds.28242

Entities

People

• Anumantha G Kanthasamy
• Arthi Kanthasamy
• Charles H. Adler
• Geidy E. Serrano
• Huajun Jin
• Naveen Kondru
• Sireesha Manne
• Thomas G. Beach
• Vellareddy Anantharam

Organizations

• Banner Sun Health Research Institute
• Iowa State University
• Mayo Clinic
• National Institutes of Health
• United States Department of Defense

Tags

Fields of Study

• Biology
• Medicine

Readers

• Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
• Oncology and Biomarker-Based Cancer Detection.
• Trauma Surgery or Emergency Medicine.