Is Levodopa Response a Valid Indicator of Parkinson's Disease?

Abstract

The clinical diagnosis of Parkinson's disease (PD) requires the presence of parkinsonism and supportive criteria that include a clear and dramatic beneficial response to dopaminergic therapy. Our aim was to test the diagnostic criterion of dopaminergic response by evaluating its association with pathologically confirmed diagnoses in a large population of parkinsonian patients.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 30, 2020
Source ID
10.1002/mds.28406

Entities

People

  • Albert A Davis
  • Baijayanta Maiti
  • Brad A Racette
  • Joel S Perlmutter
  • Johanna Hartlein
  • Michael Miles
  • Mwiza Ushe
  • Nigel J. Cairns
  • Paul T. Kotzbauer
  • Qiaonan Zhong
  • Richard J Perrin
  • Scott A Norris
  • Susan Criswell
  • W.r. Wayne Martin

Organizations

  • American Parkinson Disease Association
  • Mayo Clinic
  • National Institute of Environmental Health Sciences
  • National Institutes of Health
  • St. Louis American Parkinson Disease Association
  • The Michael J. Fox Foundation
  • United States Department of Defense
  • University of Alberta
  • University of Exeter
  • University of the Witwatersrand
  • Washington University in St. Louis

Tags

Fields of Study

  • Medicine
  • Psychology

Readers

  • Instructional Design and Training Evaluation.
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Oncology