The limitations of qPCR telomere length measurement in diagnosing dyskeratosis congenita
Abstract
Telomere length <1st percentile‐for‐age in leukocyte subsets by flow cytometry with fluorescence in situ hybridization (flow FISH) is highly sensitive and specific in diagnosing patients with dyskeratosis congenita (DC), a telomere biology disorder.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 20, 2016
- Source ID
- 10.1002/mgg3.220
Entities
People
- Blanche P Alter
- Hormuzd A. Katki
- Immaculata De Vivo
- Jack A Yanovski
- Jason Y. Y. Wong
- Joan C. Han
- Neelam Giri
- Payal P. Khincha
- Shahinaz Gadalla
- Sharon A. Savage
- Stephen R. Spellman
Organizations
- Center for International Blood and Marrow Transplant Research
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Harvard Medical School
- Harvard T.H. Chan School of Public Health
- National Cancer Institute
- National Heart, Lung, and Blood Institute
- National Institute of Allergy and Infectious Diseases
- National Institutes of Health
- Office of Naval Research
- University of Tennessee Health Science Center