Integration of deployable fluid lenses and reflectors with endoluminal therapeutic ultrasound applicators: Preliminary investigations of enhanced penetration depth and focal gain
Abstract
Catheter‐based ultrasound applicators can generate thermal ablation of tissues adjacent to body lumens, but have limited focusing and penetration capabilities due to the small profile of integrated transducers required for the applicator to traverse anatomical passages. This study investigates a design for an endoluminal or laparoscopic ultrasound applicator with deployable acoustic reflector and fluid lens components, which can be expanded after device delivery to increase the effective acoustic aperture and allow for deeper and dynamically adjustable target depths. Acoustic and biothermal theoretical studies, along with benchtop proof‐of‐concept measurements, were performed to investigate the proposed design.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 08, 2017
- Source ID
- 10.1002/mp.12458
Entities
People
- Chris J. Diederich
- Graham Sommer
- Matthew S. Adams
- Serena J. Scott
- Vasant A. Salgaonkar
Organizations
- Air Force Office of Scientific Research
- National Institutes of Health
- Stanford University
- United States Department of Defense
- University of California, Berkeley
- University of California, San Francisco