Detection of in vivo enzyme activity with CatalyCEST MRI

Abstract

CatalyCEST MRI compares the detection of an enzyme‐responsive chemical exchange saturation transfer (CEST) agent with the detection of an unresponsive “control” CEST agent that accounts for other conditions that influence CEST. The purpose of this study was to investigate the feasibility of in vivo catalyCEST MRI.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 02, 2013
Source ID
10.1002/mrm.24763

Entities

People

  • Amanda F. Baker
  • Byunghee Yoo
  • Carlos T. Pineda
  • Christine M. Howison
  • Erin A. Maine
  • Mark D. Pagel
  • Matthew J. K. Douglas
  • Vipul R. Sheth

Organizations

  • Case Western Reserve University
  • Massachusetts Institute of Technology
  • National Institutes of Health
  • United States Army Medical Research and Development Command
  • University of Arizona

Tags

Readers

  • Cardiovascular Physiology
  • Neurotoxicology
  • Trauma or Military Medicine