Volumetric spiral chemical shift imaging of hyperpolarized [2‐13c]pyruvate in a rat c6 glioma model
Abstract
MRS of hyperpolarized [2‐13C]pyruvate can be used to assess multiple metabolic pathways within mitochondria as the 13C label is not lost with the conversion of pyruvate to acetyl‐CoA. This study presents the first MR spectroscopic imaging of hyperpolarized [2‐13C]pyruvate in glioma‐bearing brain.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 06, 2015
- Source ID
- 10.1002/mrm.25766
Entities
People
- Daniel M. Spielman
- Dirk Mayer
- Jae Mo Park
- Lawrence D. Recht
- Milton Merchant
- Ralph E. Hurd
- Ron Watkins
- Sonal Josan
- Taichang Jang
Organizations
- GE HealthCare
- Lucas Foundation
- National Institutes of Health
- SRI International
- Stanford University
- United States Department of Defense