Incorporating dixon multi‐echo fat water separation for novel quantitative magnetization transfer of the human optic nerve in vivo
Abstract
The optic nerve (ON) represents the sole pathway between the eyes and brain; consequently, diseases of the ON can have dramatic effects on vision. However, quantitative magnetization transfer (qMT) applications in the ON have been limited to ex vivo studies, in part because of the fatty connective tissue that surrounds the ON, confounding the magnetization transfer (MT) experiment. Therefore, the aim of this study was to implement a multi‐echo Dixon fat‐water separation approach to remove the fat component from MT images.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2016
- Source ID
- 10.1002/mrm.26164
Entities
People
- Alex K Smith
- Bailey D. Lyttle
- E. Brian Welch
- Hakmook Kang
- Lindsey M. Dethrage
- Richard D. Dortch
- Seth A. Smith
Organizations
- United States Department of Defense
- Vanderbilt University