Using bidirectional chemical exchange for improved hyperpolarized [13C]bicarbonate pH imaging
Abstract
Rapid chemical exchange can affect SNR and pH measurement accuracy for hyperpolarized pH imaging with [13C]bicarbonate. The purpose of this work was to investigate chemical exchange effects on hyperpolarized imaging sequences to identify optimal sequence parameters for high SNR and pH accuracy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 03, 2019
- Source ID
- 10.1002/mrm.27780
Entities
People
- Celine Baligand
- Daniel B. Vigneron
- David Korenchan
- David M Wilson
- Jeremy W Gordon
- John Kurhanewicz
- Mark Vancriekinge
- Peder E.z. Larson
- Renuka Sriram
- Robert Bok
- Robert R Flavell
- Sukumar Subramaniam
Organizations
- Alternative Energies and Atomic Energy Commission
- National Cancer Institute
- National Institute of Biomedical Imaging and Bioengineering
- Prostate Cancer Foundation
- United States Department of Defense
- University of California, San Francisco