Optimal mass transport kinetic modeling for head and neck DCE‐MRI: Initial analysis

Abstract

Current state‐of‐the‐art models for estimating the pharmacokinetic parameters do not account for intervoxel movement of the contrast agent (CA). We introduce an optimal mass transport (OMT) formulation that naturally handles intervoxel CA movement and distinguishes between advective and diffusive flows.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 04, 2019
Source ID
10.1002/mrm.27897

Entities

People

  • Allen Tannenbaum
  • Amita Shukla‐dave
  • Eve LoCastro
  • Joseph O. Deasy
  • Nancy Y. Lee
  • Ramesh Paudyal
  • Rena Elkin
  • Saad Nadeem
  • Vaios Hatzoglou

Organizations

  • Air Force Office of Scientific Research
  • Memorial Sloan Kettering Cancer Center
  • National Institutes of Health
  • Stony Brook University
  • The Breast Cancer Research Foundation

Tags

Readers

  • Combustion and Flow Dynamics.
  • Medical Imaging.
  • Naval Architecture and Marine Engineering.