Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy

Abstract

The goal of this study was to combine a specialized acquisition method with a new quantification pipeline to accurately and efficiently probe the metabolism of hyperpolarized 13C‐labeled compounds in vivo. In this study, we tested our approach on [2‐13C]pyruvate and [1‐13C]α‐ketoglutarate data in rat orthotopic brain tumor models at 3T.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 14, 2021
Source ID
10.1002/mrm.29081

Entities

People

  • Anne Marie Gillespie
  • Donghyun Hong
  • Georgios Batsios
  • Manushka V Vaidya
  • Pavithra Viswanath
  • Peder Larson
  • Sabrina M. Ronen

Organizations

  • American Cancer Society
  • United States Department of Defense
  • University of California, San Francisco

Tags

Readers

  • Medical Imaging.