Obligatory role of Schwann cell‐specific erythropoietin receptors in erythropoietin‐induced functional recovery and neurogenic muscle atrophy after nerve injury

Abstract

Erythropoietin (EPO) promotes myelination and functional recovery in rodent peripheral nerve injury (PNI). While EPO receptors (EpoR) are present in Schwann cells, the role of EpoR in PNI recovery is unknown because of the lack of EpoR antagonists or Schwann cell‐specific EpoR knockout animals.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 01, 2020
Source ID
10.1002/mus.27121

Entities

People

  • Anagha A. Gurjar
  • Grant D. Wandling
  • John C Elfar
  • John P. Hegarty
  • Jung Il Lee
  • M. A. Hassan Talukder
  • Mary O’brien
  • Prem Kumar Govindappa
  • Zara Karuman

Organizations

  • Hanyang University
  • Pennsylvania State University
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Materials Science (Mechanical Engineering).
  • Molecular and Cellular Biology
  • Neurotrauma and Rehabilitation Medicine.