Multiple sessions of therapeutic electrical stimulation using implantable thin‐film wireless nerve stimulators improve functional recovery after sciatic nerve isograft repair
Abstract
Although therapeutic electrical stimulation (TES) of injured peripheral nerve promotes axon regeneration and functional recovery, clinical applications of this therapy are limited to the intraoperative timeframe. Implantable, thin‐film wireless nerve stimulators offer a potential solution to this problem by enabling delivery of electrical stimuli to an injured nerve over a period of several days post‐surgery. The aim of this study was to determine the optimal time course of stimulation for maximizing functional recovery in a rat sciatic nerve isograft repair model.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 17, 2023
- Source ID
- 10.1002/mus.27776
Entities
People
- Arman Odabas
- Matthew R. Macewan
- Nathan Birenbaum
- Nikhil S. Chandra
- Wilson Z. Ray
- Ying Yan
Organizations
- United States Department of Defense
- Washington University in St. Louis