Carbon Monoxide and Exercise Prevents Diet‐Induced Obesity and Metabolic Dysregulation Without Affecting Bone
Abstract
Carbon monoxide (CO) may counteract obesity and metabolic dysfunction in rodents consuming high‐fat diets, but the skeletal effects are not understood. This study investigated whether low‐dose inhaled CO (250 ppm) with or without moderate intensity aerobic exercise (3 h/wk) would limit diet‐induced obesity and metabolic dysregulation and preserve bone health.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2020
- Source ID
- 10.1002/oby.22768
Entities
People
- Claude A. Piantadosi
- Corrine E. Metzger
- Elizabeth A. Swallow
- Erin M. Mcnerny
- Heath G Gasier
- Joshua M. Swift
- Matthew R. Allen
- Tianzheng Yu
Organizations
- Defense Health Agency
- Duke University
- Indiana University
- Uniformed Services University of the Health Sciences