Cumulative effect of five genetic variants on prostate cancer risk in multiple study populations

Abstract

A strong cumulative effect of five genetic variants and family history on prostate cancer risk was recently reported in a Swedish population (CAPS). We carried out this study to confirm the finding in two U.S. study populations and perform a combined analysis to obtain a more stable estimate of the odds ratio (OR) for prostate cancer.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 19, 2008
Source ID
10.1002/pros.20793

Entities

People

  • Alan W. Partin
  • Bao‐li Chang
  • Bruce J Trock
  • David Duggan
  • Fredrik Wiklund
  • Henrik Grönberg
  • Jianfeng Xu
  • Jielin Sun
  • John D. Carpten
  • Kathleen E. Wiley
  • Patrick C. Walsh
  • Pär Stattin
  • S. Lilly Zheng
  • Sarah D. Isaacs
  • William B Isaacs

Organizations

  • National Cancer Institute
  • Swedish Cancer Society
  • United States Department of Defense

Tags

Readers

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Technology Areas

  • Biotechnology