Comparison of ACINUS, caspase‐3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis
Abstract
The balance between apoptotic and proliferative processes determines the enlargement of a tumor. Accurate measurement of apoptotic and proliferative rates from diagnostic prostate biopsies would allow calculation of tumor growth rates in a population‐based prostate cancer (CaP) study. Automated image analysis may be used if proliferation and apoptotic biomarkers provide clearly resolved immunostained images.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 30, 2009
- Source ID
- 10.1002/pros.21019
Entities
People
- Anastasia Ivanova
- D. Antony Jeyaraj
- Diana C. Mehedint
- Elena A. Pop
- Gregory E. Wilding
- James L Mohler
- O. Harris Ford Iii
- Rameela Chandrasekhar
- Susan J. Maygarden
- Swaroop S. Singh
Organizations
- Roswell Park Comprehensive Cancer Center
- United States Department of Defense