Association of CD14 variant with prostate cancer in African American men
Abstract
African American men have the highest rates of prostate cancer worldwide, and immunogenetic studies suggest that people of African descent have increased susceptibility to diseases of inflammation. Since genetic susceptibility is an etiological factor in prostate cancer, we hypothesize that sequence variants in the promoter region of the CD14 gene that regulate inflammation may modify individual susceptibility to this disease.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 14, 2009
- Source ID
- 10.1002/pros.21060
Entities
People
- Chiledum Ahaghotu
- George Bonney
- Georgia M. Dunston
- Jessy Joykutty
- Luisel Ricks‐santi
- Rick Kittles
- Tshela E. Mason
- Victor Apprey
- Weidong Chen
Organizations
- National Institutes of Health
- United States Department of Defense