Human prostate sphere‐forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo
Abstract
Prostate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications. Cells from dissociated tissues that form spheres in vitro often represent stem/progenitor cells. A subset of human prostate cells that form prostaspheres were evaluated for self‐renewal and tissue regeneration capability in the present study.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 24, 2009
- Source ID
- 10.1002/pros.21083
Entities
People
- Andrew S Goldstein
- Bao Zhang
- Chau P. Tran
- Christian S. Head
- Isla P Garraway
- Maahum Haider
- Mark A. Rubin
- Owen N Witte
- Robert E. Reiter
- Scott A. Hahm
- Sven Perner
- Wenyi Sun
Organizations
- Jean Perkins Foundation
- Jonsson Comprehensive Cancer Center
- National Institutes of Health
- Prostate Cancer Foundation
- UCLA David Geffen School of Medicine
- United States Department of Defense