Prostate cancer risk‐associated variants reported from genome‐wide association studies: Meta‐analysis and their contribution to genetic Variation

Abstract

Genome‐wide association studies (GWAS) have led to the discovery of multiple single nucleotide polymorphisms (SNPs) that are associated with prostate cancer (PCa) risk. These SNPs may potentially be used for risk prediction. To date, there is not a stable estimate of their effect on PCa risk and their contribution to the genetic variation both of which are important for future risk prediction.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 16, 2010
Source ID
10.1002/pros.21208

Entities

People

  • A. Karim Kader
  • Fang‐chi Hsu
  • Jianfeng Xu
  • Jielin Sun
  • S. Lilly Zheng
  • Seong‐tae Kim
  • Tao Jin
  • William B Isaacs
  • Yu Cheng

Organizations

  • National Cancer Institute
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.
  • Prostate Cancer Biology.

Technology Areas

  • Biotechnology