Functional annotation of risk loci identified through genome‐wide association studies for prostate cancer
Abstract
The majority of established prostate cancer (PCa) risk‐associated single nucleotide polymorphisms (SNPs) identified from genome‐wide association studies do not fall into protein coding regions. Therefore, the mechanisms by which these SNPs affect PCa risk remain unclear. Here, we used a series of bioinformatic tools and databases to provide possible molecular insights into the actions of risk SNPs.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 06, 2010
- Source ID
- 10.1002/pros.21311
Entities
People
- Hongjie Yu
- Jianfeng Xu
- Jielin Sun
- S. Lily Zheng
- William B Isaacs
- Yizhen Lu
- Zheng Zhang
Organizations
- National Cancer Institute
- United States Department of Defense