Chromosome 8q24 variants are associated with prostate cancer risk in a high risk population of African ancestry
Abstract
Earlier studies on the role of germline variations in the disproportionate higher burden of prostate cancer in men of African ancestry have been largely unrewarding. However, the successful replication of recent genome‐wide association findings implicating some regions of chromosome 8q24 in the disparate prostate cancer susceptibility in men of European and African ancestry have been encouraging. This case–control study was designed to evaluate the association between germline variations in chromosome 8q24 and prostate cancer risk in Afro‐Caribbean Tobago men, a population of predominantly West African ancestry.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 12, 2011
- Source ID
- 10.1002/pros.21320
Entities
People
- Alan L. Patrick
- Clareann H. Bunker
- Joseph M. Zmuda
- Michael N. Okobia
- Robert E. Ferrell
Organizations
- National Cancer Institute
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- United States Department of Defense