LNCaP prostate cancer cells with autocrine interleukin‐6 expression are resistant to IL‐6‐induced neuroendocrine differentiation due to increased expression of suppressors of cytokine signaling
Abstract
Neuroendocrine differentiation (NED) is one of the mechanisms underlying development of castration‐resistant prostate cancer (CRPC). In this study, we investigated IL‐6‐induced NED in two LNCaP sublines.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 27, 2011
- Source ID
- 10.1002/pros.22479
Entities
People
- Allen C Gao
- Dongxia Ge
- Qiuyang Zhang
- Sen Liu
- Yun Xue
- Zongbing You
Organizations
- National Institutes of Health
- United States Department of Defense