Genetic polymorphism and prostate cancer aggressiveness: A case‐only study of 1,536 GWAS and candidate SNPs in African‐Americans and European‐Americans
Abstract
Genome‐wide association studies have established a number of replicated single nucleotide polymorphisms (SNPs) for susceptibility to prostate cancer (CaP), but it is unclear whether these susceptibility SNPs are also associated with disease aggressiveness. This study evaluates whether such replication SNPs or other candidate SNPs are associated with CaP aggressiveness in African‐American (AA) and European‐American (EA) men.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 01, 2012
- Source ID
- 10.1002/pros.22532
Entities
People
- Elizabeth T.h. Fontham
- Gary J. Smith
- Jack A. Taylor
- James L Mohler
- Jeannette T. Bensen
- Zongli Xu
Organizations
- United States Department of Defense