Increased association of the ERG oncoprotein expression in advanced stages of prostate cancer in Filipinos
Abstract
Filipinos with prostate cancer (CaP) are at increased risk of harboring advanced stages and lower survival rates compared to other Asians. This study aims to investigate prevalence of ETS‐related gene (ERG) oncoprotein overexpression in Filipinos as surrogate of TMPRSS2‐ERG gene fusions, using a highly specific monoclonal antibody (ERG‐MAb), and conduct the first attempt to study the role of genetic alterations in the aggressive tumor biologic behaviour of CaP among Filipinos.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 09, 2014
- Source ID
- 10.1002/pros.22791
Entities
People
- Aladin B. Plaza
- Eliza M. Raymundo
- Isabell A. Sesterhenn
- Jesus Emmanuel Sevilleja
- Marie Carmela M. Lapitan
- Michele H. Diwa
- Shiv Srivastava
Organizations
- Institute of Molecular Biology
- Joint Pathology Center
- Uniformed Services University of the Health Sciences