IL‐17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44‐VCAM‐1 interaction
Abstract
Extravasation is a critical step in cancer metastasis, in which adhesion of intravascular cancer cells to the vascular endothelial cells is controlled by cell surface adhesion molecules. The role of interleukin‐17 (IL‐17), insulin, and insulin‐like growth factor 1 (IGF1) in adhesion of prostate cancer cells to the vascular endothelial cells is unknown, which is the subject of the present study.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 14, 2015
- Source ID
- 10.1002/pros.22971
Entities
People
- Chong Chen
- Damir B. Khismatullin
- Hui Zhang
- Jiandong Mei
- Keshab R. Parajuli
- Qiuyang Zhang
- Sen Liu
- Yine Qu
- Zhiquan Chen
- Zongbing You
Organizations
- National Institutes of Health
- Sichuan University
- Tulane University of Louisiana
- United States Department of Defense