Targeting Th17‐IL‐17 Pathway in Prevention of Micro‐Invasive Prostate Cancer in a Mouse Model
Abstract
Chronic inflammation has been associated with the development and progression of human cancers including prostate cancer. The exact role of the inflammatory Th17‐IL‐17 pathway in prostate cancer remains unknown. In this study, we aimed to determine the importance of Th17 cells and IL‐17 in a Pten‐null prostate cancer mouse model.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 27, 2017
- Source ID
- 10.1002/pros.23343
Entities
People
- David M. Cunningham
- Dongxia Ge
- Feng Huang
- Lin Ma
- Qiuyang Zhang
- Sen Liu
- Thomas P. Burris
- Zongbing You
Organizations
- National Institute of General Medical Sciences
- National Institutes of Health
- Saint Louis University
- Shaanxi University of Chinese Medicine
- Sichuan University
- Tulane University of Louisiana
- United States Department of Defense