Rare germline mutations in African American men diagnosed with early‐onset prostate cancer

Abstract

African Americans have both a higher incidence of prostate cancer and greater disease‐specific mortality compared with non‐Hispanic whites. Historically, the investigation of the contribution of rare genetic variants to prostate cancer in African American men has been hampered by low participation in large genetic studies, particularly those focused on early‐onset and familial disease.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 21, 2018
Source ID
10.1002/pros.23464

Entities

People

  • Anna M. Johnson
  • Daniel Liesman
  • Jennifer L Beebe-Dimmer
  • Kathleen A. Cooney
  • Kimberly A. Zuhlke

Organizations

  • Barbara Ann Karmanos Cancer Institute
  • United States Department of Defense
  • University of Michigan
  • University of Utah
  • Wayne State University

Tags

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology