Germline mutations in PPFIBP2 are associated with lethal prostate cancer
Abstract
Few genes have germline mutations which predispose men to more aggressive prostate cancer (PCa). This study evaluated the contribution of germline loss of function (LOF) variants in PPFIBP2 to risk of lethal PCa.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 24, 2018
- Source ID
- 10.1002/pros.23697
Entities
People
- Ashley L. Kapron
- Bingjian Feng
- Brian T. Helfand
- Charles M. Ewing
- Herbert Ballentine Carter
- Hongjie Yu
- Jianfeng Xu
- Julie L. Boyle
- Jun Luo
- Kathleen A. Cooney
- Kathleen E. Wiley
- Patrick C. Walsh
- Rong Na
- Sameep Shah
- Siqun Lilly Zheng
- William B Isaacs
- Yishuo Wu
- Zhuqing Shi
Organizations
- Fudan University
- Johns Hopkins University
- NorthShore University HealthSystem
- Shanghai Jiao Tong University
- United States Department of Defense
- University of Utah