Sox7 negatively regulates prostate‐specific membrane antigen (PSMA) expression through PSMA‐enhancer
Abstract
PSMA expression in the prostate epithelium is controlled by a cis‐element, PSMA enhancer (PSME). PSME contains multiple binding sites for Sox proteins, and in this study, we identified Sox7 protein as a negative regulator of PSMA expression through its interaction with PSME.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 28, 2018
- Source ID
- 10.1002/pros.23743
Entities
People
- Chun‐gen Xing
- Jin‐tang Dong
- Lizheng Guo
- Peng Wei
- Rui Jin
- Ruoyi Tang
- Wei Zhou
- Xiuju Liu
Organizations
- American Cancer Society
- Congressionally Directed Medical Research Programs
- Emory University
- National Cancer Institute
- Rollins School of Public Health
- Soochow University