Distinct expression patterns of SULT2B1b in human prostate epithelium

Abstract

SULT2B1b (sulfotransferase family cytosolic 2B member 1b) catalyzes the sulfate conjugation of substrates such as cholesterol and oxysterols. Our laboratory has previously shown that SULT2B1b inhibition modulates androgen receptor signaling and induces apoptosis in prostate cancer cells. However, the functions of SULT2B1b in the prostate remain poorly understood.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 18, 2019
Source ID
10.1002/pros.23829

Entities

People

  • Colm Morrissey
  • Douglas W. Strand
  • Jiang Yang
  • Meaghan M. Broman
  • Nadia A. Lanman
  • Paula O. Cooper
  • Timothy L Ratliff

Organizations

  • Purdue University
  • United States Department of Defense
  • University of Washington
  • Walther Cancer Foundation

Tags

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biochemistry
  • Prostate Cancer Biology.