Inflammation‐associated pathologies in a case of prostate schistosomiasis: Implications for a causal role in prostate carcinogenesis
Abstract
Urogenital infection with Schistosoma haematobium is a risk factor for the development of squamous cell carcinoma of the urinary bladder. The pathophysiology is thought to be mediated in part by inflammation, cellular damage, and bladder regeneration induced by the parasitic infection. Herein, we report an unusual case of schistosomiasis of the prostate that was found concurrent with prostate adenocarcinoma in a radical prostatectomy specimen from a man in the United States.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 18, 2019
- Source ID
- 10.1002/pros.23841
Entities
People
- Angelo M De Marzo
- Jessica Hicks
- Karen S Sfanos
- Lauren B Peiffer
- Sarah E. Ernst
- Sarah L. Poynton
Organizations
- Congressionally Directed Medical Research Programs
- Johns Hopkins University
- Sidney Kimmel Comprehensive Cancer Center