Role of Runx2 in prostate development and stem cell function

Abstract

RUNX2, a critical transcription factor in bone development, is also expressed in prostate and breast where it has been linked to cancer progression and cancer stem cells. However, its role in normal prostate biology has not been previously examined.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 07, 2021
Source ID
10.1002/pros.24099

Entities

People

  • Chunxi Ge
  • Renny T Franceschi
  • Yan Li

Organizations

  • National Institute of Dental and Craniofacial Research
  • United States Department of Defense
  • University of Michigan

Tags

Readers

  • Military Science
  • Oncology
  • Prostate Cancer Biology.

Technology Areas

  • Biotechnology