A polymorphism in the promoter of FRAS1 is a candidate SNP associated with metastatic prostate cancer

Abstract

Inflammation and one of its mediators, NF‐kappa B (NFκB), have been implicated in prostate cancer carcinogenesis. We assessed whether germline polymorphisms associated with NFκB are associated with the risk of developing lethal disease (metastases or death from prostate cancer).

Document Details

Document Type
Pub Defense Publication
Publication Date
May 06, 2021
Source ID
10.1002/pros.24148

Entities

People

  • Ana Vega
  • Anis A Hamid
  • Christopher Sweeney
  • Curtis Huttenhower
  • Daniela Börnigen
  • Frank Claessens
  • Gwo‐Shu Mary Lee
  • Huma Rana
  • Janet L. Stanford
  • Jong Y Park
  • Karina D. Sørensen
  • Kathryn L. Penney
  • Kristina M. Jordahl
  • Lorelei A. Mucci
  • Mark Pomerantz
  • Matthew L Freedman
  • Milan S. Geybels
  • Nawaid Usmani
  • Ros A. Eeles
  • Sarah C Markt
  • Sonja I. Berndt
  • The Practical Consortium
  • Timothy R Rebbeck
  • Travis Gerke
  • Victoria Wang

Organizations

  • Aarhus University
  • Broad Institute
  • Case Western Reserve University
  • Congressionally Directed Medical Research Programs
  • Dana–Farber Cancer Institute
  • H. Lee Moffitt Cancer Center & Research Institute
  • Harvard Medical School
  • Harvard T.H. Chan School of Public Health
  • Harvard University
  • Institute of Cancer Research
  • Katholieke Universiteit Leuven
  • Maastricht University
  • National Cancer Institute
  • The Royal Marsden NHS Foundation Trust
  • University Medical Center Hamburg-Eppendorf
  • University of Alberta

Tags

Readers

  • Molecular Biology and Genetics
  • Oncology and Biomarker-Based Cancer Detection.