Paracrine Wnt signaling is necessary for prostate epithelial proliferation

Abstract

The Wnt proteins play key roles in the development, homeostasis, and disease progression of many organs including the prostate. However, the spatiotemporal expression patterns of Wnt proteins in prostate cell lineages at different developmental stages and in prostate cancer remain inadequately characterized.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 11, 2022
Source ID
10.1002/pros.24298

Entities

People

  • Colm Morrissey
  • Daniel W Lin
  • Justin Daho Lee
  • Kevin Kong
  • Lawrence D. True
  • Li Xin
  • Martine P. Roudier
  • Oh‐joon Kwon
  • Peter S Nelson
  • Ruth F. Dumpit
  • Wei Xing

Organizations

  • Fred Hutchinson Cancer Center
  • National Institute of Diabetes and Digestive and Kidney Diseases
  • Prostate Cancer Foundation
  • United States Department of Defense
  • University of Washington

Tags

Readers

  • Molecular Biology and Genetics
  • Systems Analysis and Design