Multiplex immunohistochemical phenotyping of T cells in primary prostate cancer
Abstract
Most prostate cancers are “immune cold” and poorly responsive to immune checkpoint inhibitors. However, the mechanisms responsible for the lack of a robust antitumor adaptive immune response in the prostate are poorly understood, which hinders the development of novel immunotherapeutic approaches.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 21, 2022
- Source ID
- 10.1002/pros.24315
Entities
People
- Andrew Erickson
- Angelo M De Marzo
- Büşra Özbek
- Carolina Gomes‐alexandre
- Gunes Guner
- Igor D. Vidal
- Janis M. Taube
- Jessica Hicks
- Karen S Sfanos
- Onur Ertunç
- Srinivasan Yegnasubramanian
- Tracy Jones
Organizations
- Bloomberg L.P.
- Johns Hopkins University
- Sidney Kimmel Comprehensive Cancer Center
- United States Department of Defense