Localization of macrophage subtypes and neutrophils in the prostate tumor microenvironment and their association with prostate cancer racial disparities
Abstract
Black men are two to three times more likely to die from prostate cancer (PCa) than White men. This disparity is due in part to discrepancies in socioeconomic status and access to quality care. Studies also suggest that differences in the prevalence of innate immune cells and heightened function in the tumor microenvironment of Black men may promote PCa aggressiveness.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 16, 2022
- Source ID
- 10.1002/pros.24424
Entities
People
- Angelo M De Marzo
- Corinne Joshu
- Igor Vidal
- Janielle P Maynard
- Jiayun Lu
- Karen S Sfanos
- Tamara L Lotan
- Taylor N. Godwin
Organizations
- American Cancer Society
- Johns Hopkins Bloomberg School of Public Health
- Johns Hopkins University
- Prostate Cancer Foundation
- Sidney Kimmel Comprehensive Cancer Center
- United States Department of Defense