Differential impact of PI3K/AKT/mTOR signaling on tumor initiation and progression in animal models of prostate cancer

Abstract

The PI3K/AKT/mTOR signaling pathway is essential for initiation and progression of prostate cancer. However, there has been no a comprehensive comparison for the role of these signaling nodes in prostate tumor initiation and progression.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 26, 2022
Source ID
10.1002/pros.24441

Entities

People

  • Chao Zhang
  • Haiyan Yu
  • Lizhong Wang
  • Michael H. Chen
  • Runhua Liu
  • Shuaibin Wang
  • Zhifang Xu

Organizations

  • United States Department of Defense
  • University of Alabama at Birmingham

Tags

Readers

  • Computational Modeling and Simulation
  • Molecular Biology and Genetics