Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry
Abstract
Although men of African ancestry (AA) have the highest mortality rate from prostate cancer (PCa), relatively little is known about the germline variants that are associated with PCa risk in AA men. The goal of this study is to systematically evaluate rare, recurrent nonsynonymous variants across the exome for their association with PCa in AA men.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 25, 2022
- Source ID
- 10.1002/pros.24477
Entities
People
- Andrew S. Rifkin
- Azita Sadeghpour
- Brian T. Helfand
- Christopher Sample
- David Moon.
- Guifang Yan
- Jennifer Beebe‐dimmer
- Jianfeng Xu
- Jun Wei
- Kathleen A. Cooney
- Marta Gielzak
- Patrick C. Walsh
- S. Lilly Zheng
- Sodam Choi
- William B Isaacs
- Zhuqing Shi
Organizations
- Duke University
- Johns Hopkins School of Medicine
- United States Department of Defense
- University of Chicago
- Wayne State University