Super‐Absorbent Polymer Valves and Colorimetric Chemistries for Time‐Sequenced Discrete Sampling and Chloride Analysis of Sweat via Skin‐Mounted Soft Microfluidics
Abstract
This paper introduces super absorbent polymer valves and colorimetric sensing reagents as enabling components of soft, skin‐mounted microfluidic devices designed to capture, store, and chemically analyze sweat released from eccrine glands. The valving technology enables robust means for guiding the flow of sweat from an inlet location into a collection of isolated reservoirs, in a well‐defined sequence. Analysis in these reservoirs involves a color responsive indicator of chloride concentration with a formulation tailored to offer stable operation with sensitivity optimized for the relevant physiological range. Evaluations on human subjects with comparisons against ex situ analysis illustrate the practical utility of these advances.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 02, 2018
- Source ID
- 10.1002/smll.201703334
Entities
People
- Adam J. Strang
- Ahyeon Koh
- Amay J Bandodkar
- Claude C. Grigsby
- Jahyun Koo
- Jennifer A. Martin
- Jeong Min Jane Park
- Jeong Sook Ha
- Jeonghyun Kim
- John A. Rogers
- Jungil Choi
- Kaitlyn E. Crawford
- Kyu‐tae Lee
- Rhonda L. Pitsch
- Sang Min Won
- Sean W. Harshman
- Seung Wook Kim
- Shuai Xu
- Sung Bong Kim
- Tyler R. Ray
- Yeguang Xue
- Yi Zhang
- Yonggang Huang
- Yurina Sekine
- Yu‐yu Chen
Organizations
- 711th Human Performance Wing
- Air Force Research Laboratory
- Binghamton University
- Duke University
- Korea University
- Kwangwoon University
- Ministry of Trade, Industry and Energy
- National Institutes of Health
- National Science Foundation
- Northwestern University
- University of Central Florida
- University of Illinois Urbana–Champaign