Patch Materials for Pulmonary Artery Arterioplasty and Right Ventricular Outflow Tract Augmentation: A Review

Abstract

Patch augmentation of the right ventricular outflow tract (RVOT) and pulmonary artery (PA) arterioplasty are relatively common procedures in the surgical treatment of patients with congenital heart disease. To date, several patch materials have been applied with no agreed upon clinical standard. Each patch type has unique performance characteristics, cost, and availability. There are limited data describing the various advantages and disadvantages of different patch materials. We performed a review of studies describing the clinical performance of various RVOT and PA patch materials and found a limited but growing body of literature. Short-term clinical performance has been reported for a multitude of patch types, but comparisons are limited by inconsistent study design and scarce histologic data. Standard clinical criteria for assessment of patch efficacy and criteria for intervention need to be applied across patch types. The field is progressing with improvements in outcomes due to newer patch technologies focused on reducing antigenicity and promoting neotissue formation which may have the ability to grow, remodel, and repair.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 07, 2023
Source ID
10.1007/s00246-023-03152-7

Entities

People

  • Aimee K Armstrong
  • Andrew R Yates
  • Arash Salavitabar
  • Christopher K. Breuer
  • John Kelly
  • Kan K. Hor
  • Maximilian Y. Emmert
  • Michael Jimenez
  • Sergio A. Carrillo
  • Simon Hoerstrup
  • Toshiharu Shinoka
  • William E. Schwartzman

Organizations

  • National Institutes of Health
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Surface Coatings Technology.
  • Systems Analysis and Design