Development and Evaluation of a Method for Automated Detection of Spreading Depolarizations in the Injured Human Brain
Abstract
Spreading depolarizations (SDs) occur in some 60% of patients receiving intensive care following severe traumatic brain injury and often occur at a higher incidence following serious subarachnoid hemorrhage and malignant hemisphere stroke (MHS); they are independently associated with worse clinical outcome. Detection of SDs to guide clinical management, as is now being advocated, currently requires continuous and skilled monitoring of the electrocorticogram (ECoG), frequently extending over many days.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 26, 2021
- Source ID
- 10.1007/s12028-021-01228-x
Entities
People
- Anthony J. Strong
- Brandon Foreman
- Clemens Pahl
- Grant Brewer
- Jed A Hartings
- José-pedro Lavrador
- Martyn G Boutelle
- Michael Sole
- Michelle Rogers
- Sharon Jewell
- Stephen T Hobson
Organizations
- Medical Research Council
- Office Of The Under Secretary Of Defense
- Wellcome Trust