Modeling information exchange between living and artificial cells
Abstract
The tools of synthetic biology have enabled researchers to explore multiple scientific phenomena by directly engineering signaling pathways within living cells and artificial protocells. Here, we explored the potential for engineered living cells themselves to assemble signaling pathways for non‐living protocells. This analysis serves as a preliminary investigation into a potential origin of processes that may be utilized by complex living systems. Specifically, we suggest that if living cells can be engineered to direct the assembly of genetic signaling pathways from genetic biomaterials in their environment, then insight can be gained into how naturally occurring living systems might behave similarly.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 01, 2017
- Source ID
- 10.1007/s40484-017-0095-4
Entities
People
- Felicia Y Scott
- Keith C. Heyde
- Maryjoe K. Rice
- Ruihua Zhang
- Sung‐ho Paek
- Warren C Ruder
Organizations
- Air Force Office of Scientific Research
- Carnegie Mellon University
- Office of Naval Research
- University of Pittsburgh
- Virginia Tech